compensation: Up to $1000 employment type: contract non-profit organization
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The UCSF Department of Anesthesia is now recruiting healthy volunteers for a clinical trial
examining the safety and effectiveness of a new oral treatment for Acute Mountain Sickness.
Acute Mountain Sickness may occur when persons ascend rapidly to high altitudes. Symptoms
include headache, loss of appetite, fatigue, nausea/vomiting, and poor sleep. A new
medication is being tested to see if it is effective in treating these symptoms.
Potential volunteers must:
- Be healthy volunteers: ages 18 - 55 years old;
- Have a primary residence elevation of 1,000 ft or lower;
- Not ascend to altitude >10,000 ft within 4 months prior;
- Willing to participate voluntarily and to read and sign a written informed
consent in English.
- Must agree to abstinence or birth control while in the study.
- Have any personal medical history of cardiovascular, cerebrovascular
diseases or respiratory disease; digestive disease, mental disease, metabolic
disease, acute infection or anemia;
- Cannot be currently experiencing symptoms of AMS;
- Have a medical history of primary headache (including migraines);
- Have donated blood or had surgery within 3 months prior;
- Cannot take any other medications (including any dietary supplements)
within 14 days prior and throughout the study period;
- Allergy to study treatment of Danshen (Radix Saliva Miltiorrhize Bge., RSM)
- Cannot be pregnant or in lactation period;
- Must be able to pass a drug screening and cannot have recent history of
alcoholism or substance abuse;
- Cannot be participating in any other clinical trial or on an investigational drug
within 30 days prior.
- Cannot be a family member or relative of the study site staff.
The study will include a screening visit to determine eligibility, baselines sea-level
assessments in San Francisco, CA, two weeks of study medication dosing prior to going
to altitude, and one week at high altitude at the White Mountain Research Station in
We will also be holding assessments in the Sacramento/ Central Valley area. Please contact us for further details.
Study procedures will include a brief physical exam, daily medication
dosing, subject questionnaires and diary keeping, routine laboratory tests, and exercise
on a stationary bicycle.
Subjects will be compensated for their time and travel; time at
altitude will include dormitory style accommodations and all meals. The study team
will provide the study medication and travel to the study site at altitude. The study
doctors will monitor all subjects for safety during all phases of the study.
To learn more, contact the study coordinator at the email address listed.
The study is being run by the UCSF Department of Anesthesia with sponsorship from
The next study trips will be:
Contact us for more details!
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