Overview:
Our laboratory's research projects conducted at NCIRE and within the UCSF Department of Surgery focus on investigating the biology of atherosclerosis regression through the development of unique genetically engineered mouse models. Our multifaceted experimental approaches and resources offer a wide range of opportunities for career development in cardiovascular biology. Long term goals of these projects include identifying therapeutic strategies to delay the progression and accelerate the regression of atherosclerosis. For an example of the scope of our work please see: Raffai et al. Arterioscler Thromb Vasc Biol. 2005 Feb; 25(2):436-41.
We are seeking a talented and motivated individual with a strong background in molecular and cellular biology to serve as our laboratory manager and to provide experimental laboratory support to assist our postdoctoral fellows with their research projects. An ability to work independently as well as within a team environment is essential. The position will involve an extensive use of genetically engineered mice.
Responsibilities:
Isolation and expression analysis of RNA by QRT-PCR
Cell culture of primary mouse cells
Histological studies of mouse tissue (sectioning, mounting, staining, quantifying volumes)
Statistical analysis of raw data and figure output
Mouse tissue isolation, handling and working with mice
Lab management (ordering/organizing lab supplies, lab website updates)
Qualifications:
Bachelors or Masters degree in Biology or related discipline
At least 4 years of relevant laboratory experience.
Knowledge of general laboratory techniques that include: Immunoprecipitation and western blotting, RNA isolation and QRT-PCR analysis, DNA extraction and transfection into cultured cells, DNA cloning vector construction
Effective oral and written communication, analytical, and interpersonal skills
Proven ability to multi-task in a deadline oriented environment with minimal supervision
Accuracy and attention to detail required
Proficiency to work with MS Excel and Adobe Photoshop/Illustrator
To apply please visit www.ncire.org and apply for job number 2009-1383
NCIRE is pleased to be an equal opportunity employer
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